Royal Air Force Typhoon fighter aircraft have operated alongside French aircraft in a combined operation on an underground arms cache in Syrian territory employed by the Daesh militant organization, as stated by the UK's MoD.
The location, located using reconnaissance, was assessed as containing munitions and bombs, the announcement noted, and was situated in mountainous terrain just above Palmyra in the heart of Syria.
"Our aircraft used laser-guided Paveway IV weapons to strike a series of approach shafts down to the site... initial indications are that the target was engaged successfully," the MoD said.
There was no sign of any civilian impact in the attack late on Saturday and all the aircraft made a safe return, the ministry further stated.
The Typhoon fighters were assisted by a Voyager aerial refuelling aircraft.
IS - referred to as Daesh - enforced extremist governance over significant areas in Syria and Iraq until 2019.
"This operation shows the UK's leading role, and commitment to work closely with our allies, to eliminate any re-emergence of Daesh and their dangerous and violent ideologies in the area," Britain's Defence Chief John Healey remarked.
British military aircraft have performed patrols over Syrian airspace to "prevent any attempted resurgence" of the group following its military defeat at the Baghuz confrontation in 2019, the ministry said.
"I want to thank all the members of the UK armed forces participating in this operation for their skill and their courage," he said. "Including them were a great many British personnel on duty over the holidays. This mission, to eliminate terrorist threats who pose a risk to our security, demonstrates how our armed forces are prepared to act, continuously, keeping Britain secure within its borders and influential overseas."
In December, the American forces executed what it termed a "large-scale strike" on IS targets in the country, following an attack resulted in the deaths of two American soldiers and a local interpreter in Palmyra.
The U.N. estimates Islamic State still maintains roughly 5-7 thousand militants in both countries.